Prognathodon constitutes one of the largest-bodied mosasaur genera, with the largest known skull (belonging to P. currii) exceeding 140 cm in length. Despite its massive size, remains of the genus are often fragmentary and incomplete. To date, very few specimens are known with articulated skulls and none with an entire skeleton.[2] Though many species were large with sizes approaching or potentially exceeding 10 m (33 ft), such as P. currii, P. saturator and P. overtoni,[2] many species were considerably smaller in size. The type species, P. solvayi, was the smallest, barely reaching 5 m (16 ft) in length.[3] Considering the 2002 study from Christiansen & Bonde, the 2013 study presents that P. saturator could have reached 12 m (39 ft) in length, while Liodon sectorius (assigned as P. sectorius) reached 8 m (26 ft) in length.[4] In 2022, Gregory S. Paul proposed that P. overtoni reached 8 metres (26 ft) in length and 1 metric ton (1.1 short tons) in body mass, while P. currii reached 11 metres (36 ft) in length and 2.8 metric tons (3.1 short tons) in body mass